Molecular and Cell Biology: Immunology and Pathogenesis

University of California, Berkeley

About the Program

Bachelor of Arts (BA)

The major in Molecular and Cell Biology: Immunology & Pathogenesis (IMP) emphasis focuses on understanding how the immune system combats infection and the mechanisms by which infectious microbial pathogens cause disease. It is now clear that inappropriate immune or inflammatory responses underlie many human diseases, and new cancer therapies exploit the immune system’s ability to recognize and eliminate tumor cells. Thus, immunology truly is at the forefront of modern biomedical science, and the undergraduate tracks within this emphasis are ideal for students interested in the medical and health sciences.

This major program has two tracks—Track 1: Immunology and Track 2: Infectious Diseases. For specific information regarding the requirements for each track, please see the Major Requirements tab on this page.

Minor Program

There is no minor program in Molecular and Cell Biology.

Other Molecular and Cell Biology Majors (Emphases)

Biochemistry and Molecular Biology (BMB)
Cell and Developmental Biology (CDB)
Genetics, Genomics, & Development (GGD)
Neurobiology (NEU)

Visit Department Website

Major Requirements

Declaring the Major

MCB is not an impacted major. Therefore, the program will accept any interested student who meets the minimum course and GPA requirements and is realistically able to complete the major requirements during the student's time at UC Berkeley.

In order to declare the MCB major, students must have completed or be enrolled in BIOLOGY 1A/BIOLOGY 1AL (C or better on first midterm) and CHEM 3B (past the early drop deadline), have at least a 2.0 overall GPA, a 2.0 GPA in the lower division prerequisite courses for the major, and know which emphasis you will declare. (Note: Transfer students must have completed at least one semester at UC Berkeley and have received a 2.0 GPA in the courses that they have taken for the major). Intended MCB students are not required to have completed the math or physics requirement at the time of declaration (though the requirement must be met in order to graduate).

To start the major declaration process, students must fill out the MCB major declaration form online.

Once the declaration form has been processed, students will receive an email with instructions to come in to meet with a staff advisor. Students should bring a printed copy of their Academic Summary from CalCentral to the Undergraduate Advising Office (3060 Valley Life Sciences Building) to discuss their academic plan. When signing in, students should inform the intake adviser that they declared online. Please note that major declarations are limited during the first week of class and the first week of course enrollment Phase 1. Any restrictions will be advertised on the MCB Undergraduate homepage and in the weekly MCB-News email. 

General Guidelines

In addition to the University, campus, and college requirements, listed on the College Requirements tab, students must fulfill requirements specific to their major program and declared emphasis.

  1. All courses taken to fulfill the major requirements below must be taken for letter graded credit.
  2. No more than one upper division course may be used to simultaneously fulfill requirements for a student's major and minor programs. Double majors and simultaneous degrees are limited to a two course overlap. 
  3. Students must maintain a minimum grade point average (GPA) of at least a 2.0 GPA overall, a 2.0 GPA in the required major coursework (lower and upper division), and a 2.0 GPA in the upper division coursework for the major.

For information regarding residence requirements and unit requirements, please see the College Requirements tab.

Lower Division Requirements: All Tracks

MATH 10AMethods of Mathematics: Calculus, Statistics, and Combinatorics4
MATH 10BMethods of Mathematics: Calculus, Statistics, and Combinatorics4
Math 10A/10B is the preferred math sequence, but the MCB major will also accept Math 1A/1B
Calculus
Calculus
CHEM 1A
1AL
General Chemistry
and General Chemistry Laboratory 1
4
CHEM 3A
3AL
Chemical Structure and Reactivity
and Organic Chemistry Laboratory 2
5
CHEM 3B
3BL
Chemical Structure and Reactivity
and Organic Chemistry Laboratory 2
5
BIOLOGY 1A
1AL
General Biology Lecture
and General Biology Laboratory
5
BIOLOGY 1BGeneral Biology Lecture and Laboratory4
PHYSICS 8AIntroductory Physics 34
PHYSICS 8BIntroductory Physics 34
1

CHEM 4A may be taken place of CHEM 1A and CHEM 1AL

2

CHEM 12A and CHEM 12B may be taken place of CHEM 3A/3AL and CHEM 3B/3BL.

3

PHYSICS 7A and PHYSICS 7B can be taken in place of PHYSICS 8A and PHYSICS 8B.

Upper Division Requirements: Immunology Track

MCELLBI C100A/CHEM C130Biophysical Chemistry: Physical Principles and the Molecules of Life4
MCELLBI 110Molecular Biology: Macromolecular Synthesis and Cellular Function4
MCELLBI 104Genetics, Genomics, and Cell Biology4
or MCELLBI 140 General Genetics
MCELLBI 150Molecular Immunology4
MCELLBI 150LImmunology Laboratory4
One IMMP Elective from List C (see below)3-4

Upper Division Requirements: Infectious Diseases Track

MCELLBI 102Survey of the Principles of Biochemistry and Molecular Biology4
MCELLBI 104Genetics, Genomics, and Cell Biology4
MCELLBI 150Molecular Immunology4
MCELLBI 150LImmunology Laboratory4
One IMMP Elective from List A (see below)3-4
One IMMP Elective from List B (see below)3-4

IMP Elective A List

MCELLBI C103/PB HLTH C102/PLANTBI C103Bacterial Pathogenesis3
MCELLBI/PLANTBI C112General Microbiology4
MCELLBI/PLANTBI C114Introduction to Comparative Virology4

IMP Elective B List

MCELLBI 130Cell and Systems Biology4
MCELLBI 132Biology of Human Cancer4
MCELLBI/PLANTBI C134Chromosome Biology/Cytogenetics3
MCELLBI 135ATopics in Cell and Developmental Biology: Molecular Endocrinology3
MCELLBI 136Physiology4
MCELLBI 141Developmental Biology4
MCELLBI 143Evolution of Genomes, Cells, and Development3
MCELLBI 149The Human Genome3
MCELLBI 160Cellular and Molecular Neurobiology4
MCELLBI 161Circuit, Systems and Behavioral Neuroscience4
MCELLBI 250Advanced Immunology4

IMP Elective C List

BIO ENG 131Introduction to Computational Molecular and Cell Biology4
MCELLBI 100BBiochemistry: Pathways, Mechanisms, and Regulation4
MCELLBI C103/PB HLTH C102/PLANTBI C103Bacterial Pathogenesis3
MCELLBI/PLANTBI C112General Microbiology4
MCELLBI/PLANTBI C114Introduction to Comparative Virology4
MCELLBI 130Cell and Systems Biology4
MCELLBI 132Biology of Human Cancer4
MCELLBI/PLANTBI C134Chromosome Biology/Cytogenetics3
MCELLBI 135ATopics in Cell and Developmental Biology: Molecular Endocrinology3
MCELLBI 141Developmental Biology4
MCELLBI 149The Human Genome3
MCELLBI 250Advanced Immunology4

College Requirements

Undergraduate students in the College of Letters & Science must fulfill the following requirements in addition to those required by their major program.

For detailed lists of courses that fulfill college requirements, please review the College of Letters & Sciences page in this Guide.

Entry Level Writing

All students who will enter the University of California as freshmen must demonstrate their command of the English language by fulfilling the Entry Level Writing requirement. Fulfillment of this requirement is also a prerequisite to enrollment in all reading and composition courses at UC Berkeley. 

American History and American Institutions

The American History and Institutions requirements are based on the principle that a US resident graduated from an American university should have an understanding of the history and governmental institutions of the United States.

American Cultures

American Cultures is the one requirement that all undergraduate students at Cal need to take and pass in order to graduate. The requirement offers an exciting intellectual environment centered on the study of race, ethnicity and culture of the United States. AC courses offer students opportunities to be part of research-led, highly accomplished teaching environments, grappling with the complexity of American Culture.

Quantitative Reasoning

The Quantitative Reasoning requirement is designed to ensure that students graduate with basic understanding and competency in math, statistics, or computer science. The requirement may be satisfied by exam or by taking an approved course.

Foreign Language

The Foreign Language requirement may be satisfied by demonstrating proficiency in reading comprehension, writing, and conversation in a foreign language equivalent to the second semester college level, either by passing an exam or by completing approved course work.

Reading and Composition

In order to provide a solid foundation in reading, writing and critical thinking the College requires two semesters of lower division work in composition in sequence. Students must complete a first-level reading and composition course by the end of their second semester and a second-level course by the end of their fourth semester.

Breadth Requirements

The undergraduate breadth requirements provide Berkeley students with a rich and varied educational experience outside of their major program. As the foundation of a liberal arts education, breadth courses give students a view into the intellectual life of the University while introducing them to a multitude of perspectives and approaches to research and scholarship. Engaging students in new disciplines and with peers from other majors, the breadth experience strengthens interdisciplinary connections and context that prepares Berkeley graduates to understand and solve the complex issues of their day.

Unit Requirements

  • 120 total units, including at least 60 L&S units

  • Of the 120 units, 36 must be upper division units

  • Of the 36 upper division units, 6 must be taken in courses offered outside your major department

Residence Requirements

For units to be considered in "residence," you must be registered in courses on the Berkeley campus as a student in the College of Letters & Science. Most students automatically fulfill the residence requirement by attending classes here for four years. In general, there is no need to be concerned about this requirement, unless you go abroad for a semester or year or want to take courses at another institution or through UC Extension during your senior year. In these cases, you should make an appointment to meet an adviser to determine how you can meet the Senior Residence Requirement.

Note: Courses taken through UC Extension do not count toward residence.

Senior Residence Requirement

After you become a senior (with 90 semester units earned toward your BA degree), you must complete at least 24 of the remaining 30 units in residence in at least two semesters. To count as residence, a semester must consist of at least 6 passed units. Intercampus Visitor, EAP, and UC Berkeley-Washington Program (UCDC) units are excluded.

You may use a Berkeley Summer Session to satisfy one semester of the Senior Residence requirement, provided that you successfully complete 6 units of course work in the Summer Session and that you have been enrolled previously in the college.

Modified Senior Residence Requirement

Participants in the UC Education Abroad Program (EAP) or the UC Berkeley Washington Program (UCDC) may meet a Modified Senior Residence requirement by completing 24 (excluding EAP) of their final 60 semester units in residence. At least 12 of these 24 units must be completed after you have completed 90 units.

Upper Division Residence Requirement

You must complete in residence a minimum of 18 units of upper division courses (excluding EAP units), 12 of which must satisfy the requirements for your major.

Plan of Study

The sample plans below show a four-year plan for completing the major, taking classes only during fall and spring semesters. All of the lower division classes are offered during the summer as well. Please consult the sample plan appropriate to your track.

Please note that the sample plans below include only courses required for your major. For more detailed information regarding other requirements, including unit minimums per semester, Letters & Science Breadth requirements, Reading and Composition (R&C), and the American Cultures (AC) requirements, please see the College Requirements tab.

Example Track 1: Immunology

Program beginning in the fall semester of freshman year. 

Freshman
FallUnitsSpringUnits
MATH 10A4MATH 10B4
CHEM 1A
1AL
4BIOLOGY 1A
1AL
5
 8 9
Sophomore
FallUnitsSpringUnits
CHEM 3A
3AL
5CHEM 3B
3BL
5
BIOLOGY 1B4PHYSICS 8A4
 9 9
Junior
FallUnitsSpringUnits
MCELLBI C100A4MCELLBI 1104
PHYSICS 8B4MCELLBI 1404
 8 8
Senior
FallUnitsSpringUnits
MCELLBI 1504IMP Elective C3-4
MCELLBI 150L4 
 8 3-4
Total Units: 62-63

Example Track 2: Infectious Diseases

Program beginning in the fall semester of freshman year. 

Freshman
FallUnitsSpringUnits
MATH 10A4MATH 10B4
CHEM 1A
1AL
4BIOLOGY 1A
1AL
5
 8 9
Sophomore
FallUnitsSpringUnits
CHEM 3A
3AL
5CHEM 3B
3BL
5
PHYSICS 8A4PHYSICS 8B4
 9 9
Junior
FallUnitsSpringUnits
MCELLBI 1024MCELLBI 1044
BIOLOGY 1B4IMP Elective A3-4
 8 7-8
Senior
FallUnitsSpringUnits
MCELLBI 1504IMP Elective B3-4
MCELLBI 150L4 
 8 3-4
Total Units: 61-63

Sample Program Plan, Spring Start

Example of program beginning in the spring semester of freshman year (e.g., FPF or Global Edge).

Freshman
FallUnitsSpringUnits
MATH 1A4MATH 1B4
 CHEM 1A
1AL
4
 4 8
Sophomore
FallUnitsSpringUnits
BIOLOGY 1A
1AL
5CHEM 3A
3AL
5
PHYSICS 8A4BIOLOGY 1B4
 9 9
Junior
FallUnitsSpringUnits
CHEM 3B
3BL
5MCELLBI 102 or C100A4
PHYSICS 8B4IMP Elective (Track-dependent)3-4
 9 7-8
Senior
FallUnitsSpringUnits
MCELLBI 104 or 140 (track-dependent)4MCELLBI 1504
MCELLBI 110 (or IMP Elective; track-dependent)4MCELLBI 150L4
 8 8
Total Units: 62-63

Sample Program Plan, Transfers

Example of program plan for students planning to transfer to Berkeley after completing all the lower division requirements.

Junior
FallUnitsSpringUnits
MCELLBI 102 or C100A4MCELLBI 104 or 1404
 MCELLBI 110 (or IMP Elective; track-dependent)4
 4 8
Senior
FallUnitsSpringUnits
MCELLBI 1504IMP Elective (track-dependent)3-4
MCELLBI 150L4 
 8 3-4
Total Units: 23-24

Student Learning Goals

Mission

The Department of Molecular and Cell Biology (MCB) is a large department that is subdivided into five divisions: Biochemistry, Biophysics, and Structural Biology (BBS); Cell and Developmental Biology (CDB); Genetics, Genomics and Development (GGD); Immunology and Pathogenesis (IMMP); and Neurobiology (NEU). All MCB students complete the same lower division coursework to gain critical training in biology, mathematics, chemistry, and physics. All or most lower division coursework is completed before major declaration. Upon declaring the major, MCB students choose an emphasis, or specialization, which determines the upper division core courses they will take and elective choices from which they will choose. Students can choose among several areas of specialization; emphases are broadly defined along divisional lines and allow students to focus on a more defined topic within MCB. MCB students who elect to participate in independent research may choose from sponsoring research laboratories within any MCB division, or in laboratories outside the department (other Berkeley departments, LBNL, CHORI, UCSF, biotechnology companies). The MCB major provides excellent preparation for many careers and postbaccalaureate training programs, including graduate programs and health-related professional programs (e.g., medicine, dentistry, optometry, pharmacy), science writing, law school, biotechnology, teaching, and academic research.

Learning Goals for the Major

  1. Describe basic biological concepts and principles
  2. Appreciate the different levels of biological organization, from molecules to ecosystems
  3. Understand that biology has a chemical, physical, and mathematical basis
  4. Explain the importance of the scientific method to understanding natural phenomena
  5. Effectively communicate scientific data and ideas, both orally and in writing
  6. Critically evaluate data, develop a hypothesis, and design experiments to address an interesting and novel problem
  7. Demonstrate advanced knowledge in a specialized field of molecular and cell biology

Advising

MCB offers three types of undergraduate advising: staff advisers, faculty advisers, and peer advisers.

Academic Advisers

Staff academic advisers are trained to support students and assist them in successfully completing their MCB major. They are excellent resources for questions concerning administration and academics, or finding out about other available services. Students should see a staff adviser for the following:

  • Ask questions about major requirements.
  • Ask advice about schedule planning.
  • Declare the MCB major.
  • Consult about research opportunities, graduate and professional schools, career opportunities, scholarships, and internships.
  • Get information and course control numbers (CCN's) for independent research.
  • Request general assistance, advice or information.
  • Find out about upcoming events and programs.

Staff advisers are primarily available for drop-in advising, though limited appointments are available for more complex issues such as probation, academic difficulty and readmission. Students who would like to schedule an appointment should call 510-643-8895 during drop-in advising hours.

The general email address is mcbuao@berkeley.edu which is checked daily, Monday through Friday, so students will receive an answer to questions within one business day.

Faculty Advisers

Faculty advisers are MCB professors assigned to advise students about the MCB department, its courses, research, and other academic issues. Students typically first meet with a faculty adviser when they declare an MCB major. Students should see their faculty advisers for the following:

  • Receive guidance toward achieving academic and career goals.
  • Ask questions about the content of MCB courses.
  • Ask questions about biological research and about the field of biology in general.
  • Ask for recommendations on which graduate schools to attend.
  • Review and approve major declaration plan, after speaking with a UAO staff adviser first.

For a list of advisers and their office hours, please see the department's website. Office hours listed are designated for drop-in advising unless otherwise noted. Faculty adviser office hours are effective from the first day of instruction until the final day of instruction for the fall and spring semesters. Faculty advisers are not available for office hours during winter or summer break. Students may refer to staff drop-in advising hours during summer sessions and non-instructional periods.

Peer Adviser Walk-in Services (PAWS)

Peer advisers are junior and senior MCB majors who volunteer their time to complement the UAO advising services by sharing their knowledge of and experience with lower division requirements and upper division classes, experience with student groups on campus, preparation for life beyond the BA, and use of various campus resources. To see the schedule and more information about who the peer advisers are and which courses they have taken, click here.

Academic Opportunities

Undergraduate Research

Under the guidance of a faculty member and/or research mentor, undergraduates in the MCB major may have the opportunity to work in a laboratory to gain valuable experience in scientific research. Interested students must take the initiative to make such arrangements. Over sixty percent of MCB majors work in a lab to gain valuable experience in scientific research. To get started, students should talk with classmates, peer advisers, an academic adviser, graduate student instructors (GSIs), and faculty about their interest in learning more about laboratory research. For more information on research, see How to Find a Lab Position.

Benefits of research:

  • Science is a way to figure things out, so doing research will aid students in other aspects of their life. Students ask and answer open ended questions and link seemingly disconnected pieces of information to find results that were not predicted.
  • Explore things at the cutting edge and that no one has explored before.
  • Learn tenacity, problem solving, and to be critical about the details because things have to be reproducible. 
  • Solve mysteries and experience the excitement of discovery.

Students may receive academic credit for their work by enrolling in an independent study course: MCELLBI 99/MCELLBI 199 or MCELLBI H196A/MCELLBI H196B. Enrollment applications are due in the Undergraduate Advising Office by the fifth week of each semester.

Honors Program

The MCB honors program offers exceptional senior students recognition for outstanding academic achievement and excellence in research. To graduate with honors in the major, students must satisfy the following:

  1. Complete at least two credited semesters of research including four to eight units of MCELLBI H196A and/or MCELLBI H196B (Honors Research).
  2. Have a cumulative Berkeley grade point average (GPA) of at least 3.3 in all work completed at UC Berkeley.
  3. Have at least a 3.5 GPA in the MCB major requirements, or 3.5 GPA in MCB upper division courses.
  4. Present their research in an approved forum, such as an MCB symposium, the Undergraduate Poster Session, or other scientific meeting.
  5. Write an honors thesis approved by an MCB faculty sponsor.

Additional information on the honors program is available in the Undergraduate Affairs Office and on the MCB website.

Other Research Opportunities

For additional resources for information regarding research opportunities, please see the links below:
Undergraduate Research Apprentice Program (URAP)
Scholarship Connection
Summer Research Opportunities
Office of Research

Funding for Student Research

There are a variety of ways to support student research. The department recommends attending a workshop at the Office of Undergraduate Research or looking for funding opportunities on their website or the Scholarship Connection website.

Courses

Molecular and Cell Biology: Immunology and Pathogenesis

MCELLBI 15 Current Topics in the Biological Sciences 2 Units

Terms offered: Spring 2017, Spring 2016, Spring 2015
Students in this course will critically examine modern methods of biological investigations and their social implications. Relevant literature will be used to present basic biological concepts that address the cultural, technological and health aspects of current topics in the biological sciences. Designing and evaluating scientific questions will be stressed.

Current Topics in the Biological Sciences: Read More [+]

MCELLBI C31 Big Ideas in Cell Biology 3 Units

Terms offered: Spring 2014, Spring 2012
An introduction for students who do not intend to major in biology but who wish to satisfy their breadth requirement in Biological Sciences. Some major concepts of modern biology, ranging from the role of DNA and the way cells communicate, to interactions of cells and creatures with their environment, will be discussed without jargon and with attention to their relevance in contemporary life and culture.

Big Ideas in Cell Biology: Read More [+]

MCELLBI 32 Introduction to Human Physiology 3 Units

Terms offered: Fall 2017, Summer 2017 8 Week Session, Fall 2016
A comprehensive introduction to human biology. The course will concentrate on basic mechanisms underlying human life processes, including cells and membranes; nerve and muscle function; cardiovascular, respiratory, renal, and gastrointestinal physiology; metabolism, endocrinology, and reproduction.

Introduction to Human Physiology: Read More [+]

MCELLBI 32L Introduction to Human Physiology Laboratory 2 Units

Terms offered: Fall 2017, Summer 2017 Second 6 Week Session, Fall 2016
Experiments and demonstrations are designed to amplify and reinforce information presented in 32. Exercises include investigations into the structure and function of muscle, nerve, cardiovascular, renal, respiratory, endocrine, and blood systems.

Introduction to Human Physiology Laboratory: Read More [+]

MCELLBI 38 Stem Cell Biology, Ethics and Societal Impact 3 Units

Terms offered: Not yet offered
Innovations in bioengineering and use of stem cells will significantly impact our ability to combat human disease, genetic disorders and physiological dysfunction. An understanding of human stem cell biology will be critical to make informed decisions on our health and public policy.

Stem Cell Biology, Ethics and Societal Impact: Read More [+]

MCELLBI 41 Genetics and Society 3 Units

Terms offered: Spring 2016, Spring 2013, Summer 2012 8 Week Session
Basic communication of inheritance; gene mapping; gene expression and genetic disease in animals and humans; social inheritance of genetics.

Genetics and Society: Read More [+]

MCELLBI C44 Biology for Voters 3 Units

Terms offered: Spring 2017, Spring 2015, Spring 2014
This is a Discovery Course for non-Biology majors designed to introduce lower-division college students to biology through the lens of the contemporary problems facing people, the planet and the species of the planet. Modern genetic contributions will be presented on such issues as genetic engineering of plants and animals, the emergence of new pathogens, the role of genetic variation among individuals, and the extent to which DNA is and
isn’t destiny. Each week will close with the presentation and discussion of a defining biological challenge facing the world.
Biology for Voters: Read More [+]

MCELLBI 50 The Immune System and Disease 4 Units

Terms offered: Spring 2017, Spring 2016, Spring 2015
Course will discuss how the immune system resolves, prevents, or causes disease. A general overview of the immune system will be covered in the first five weeks followed by five weeks discussing infectious diseases including anthrax, mad cow, herpes, malaria, tuberculosis, and HIV. In addition, other lectures will focus on current immunology topics including vaccines, autoimmunity, allergy, transplantation, and cancer.

The Immune System and Disease: Read More [+]

MCELLBI 55 Plagues and Pandemics 3 Units

Terms offered: Fall 2017, Fall 2016, Fall 2015
Discussion of how infectious agents cause disease and impact society at large. We will examine historical and current examples of plagues and pandemics and consider the question of what we should do to ameliorate the impact of infectious disease in the future. The course is intended for non-majors and will begin by briefly providing necessary background in microbiology and immunology. The primary focus in each subsequent week, however, will be
on discussing a particular infectious disease. The course will be broad in scope covering biological, historical, ethical and social implications of each disease.
Plagues and Pandemics: Read More [+]

MCELLBI C61 Brain, Mind, and Behavior 3 Units

Terms offered: Spring 2017, Spring 2016, Spring 2015
Introduction to human brain mechanisms of sensation, movement, perception, thinking, learning, memory, and emotion in terms of anatomy, physiology, and chemistry of the nervous system in health and disease. Intended for students in the humanities and social sciences and others not majoring in the biological sciences.

Brain, Mind, and Behavior: Read More [+]

MCELLBI W61 Brain, Mind, and Behavior 3 Units

Terms offered: Summer 2017 First 6 Week Session, Summer 2016 10 Week Session, Summer 2015 First 6 Week Session
This course deals with the structure and function of the human nervous system, with an emphasis on how brain physiology and chemistry are related to human behavior. This is a comprehensive introduction to the exciting field of contemporary neuroscience for students of all backgrounds and interests, including those from the humanities and social sciences, as well as physical and biological
sciences. The Final Examination will be administered in a proctored setting. See Schedule of Classes for meeting information. This course is web-based.
Brain, Mind, and Behavior: Read More [+]

MCELLBI C62 Drugs and the Brain 3 Units

Terms offered: Fall 2017, Fall 2015, Fall 2014
The history, chemical nature, botanical origins, and effects on the human brain and behavior of drugs such as stimulants, depressants, psychedelics, analgesics, antidepressants, antipsychotics, steroids, and other psychoactive substances of both natural and synthetic origin. The necessary biological, chemical, and psychological background material for understanding the content of this course will be contained within the course itself.

Drugs and the Brain: Read More [+]

MCELLBI 63 Introduction to Functional Neuroanatomy 3 Units

Terms offered: Summer 2017 Second 6 Week Session, Summer 2016 10 Week Session, Summer 2016 Second 6 Week Session
This course emphasizes beginning anatomy of the brain and spinal cord to individuals interested in understanding the dynamics of motor and sensory functions in the human body. Students in the Departments of Education, Psychology, and Integrative Biology, as well as students interested in medicine and the life sciences, are especially encouraged to attend.

Introduction to Functional Neuroanatomy: Read More [+]

MCELLBI C64 Exploring the Brain: Introduction to Neuroscience 3 Units

Terms offered: Summer 2017 8 Week Session, Summer 2016 10 Week Session, Summer 2016 8 Week Session, Fall 2015
This course will introduce lower division undergraduates to the fundamentals of neuroscience. The first part of the course covers basic membrane properties, synapses, action potentials, chemical and electrical synaptic interactions, receptor potentials, and receptor proteins. The second part of the course covers networks in invertebrates, memory and learning behavior, modulation, vertebrate
brain and spinal cord, retina, visual cortex architecture, hierarchy, development, and higher cortical centers.
Exploring the Brain: Introduction to Neuroscience: Read More [+]

MCELLBI 84 Sophomore Seminar 0.0 Units

Terms offered: Prior to 2007
Sophomore seminars are small interactive courses offered by faculty members in departments all across the campus. Sophomore seminars offer opportunity for close, regular intellectual contact between faculty members and students in the crucial second year. The topics vary from department to department and semester to semester. Enrollment limited to 15 sophomores.

Sophomore Seminar: Read More [+]

MCELLBI 84B Sophomore Seminar 1 or 2 Units

Terms offered: Fall 2013, Spring 2013, Fall 2012
Sophomore seminars are small interactive courses offered by faculty members in departments all across the campus. Sophomore seminars offer opportunity for close, regular intellectual contact between faculty members and students in the crucial second year. The topics vary from department to department and semester to semester. Enrollment limited to 15 sophomores.

Sophomore Seminar: Read More [+]

MCELLBI 88 Immunotherapy of Cancer: Success and Failures 2 Units

Terms offered: Spring 2017
We will work with a variety of datasets that describe a molecular view of cells and how they divide. We will learn about the processes that cause cells to become specialized (differentiate) and to give rise to cancer (transform). We will analyze data on genetic mutations in cancer that distinguish tumor cells from normal cells. We will learn how mutations are detected by the immune system and the basis of cancer immunotherapy. Finally we will analyze data on clinical
trials of cancer immunotherapy to define the correlates of success in curing the disease. The students are expected to gain an understanding of data that reveals the basics of cell physiology and cancer, how immunotherapies of cancer work and their current limitations.
Immunotherapy of Cancer: Success and Failures: Read More [+]

MCELLBI 90A Freshman Seminars: Biochemistry and Molecular Biology 1 Unit

Terms offered: Fall 2017, Spring 2017, Fall 2016
The Berkeley Seminar Program has been designed to provide new students with the opportunity to explore an intellectual topic with a faculty member in a small-seminar setting. Berkeley Seminars are offered in all campus departments, and topics vary from department to department and semester to semester.

Freshman Seminars: Biochemistry and Molecular Biology: Read More [+]

MCELLBI 90B Freshman Seminars: Cell and Developmental Biology 1 Unit

Terms offered: Fall 2017, Fall 2016, Spring 2016
The Berkeley Seminar Program has been designed to provide new students with the opportunity to explore an intellectual topic with a faculty member in a small-seminar setting. Berkeley Seminars are offered in all campus departments, and topics vary from department to department and semester to semester.

Freshman Seminars: Cell and Developmental Biology: Read More [+]

MCELLBI 90C Freshman Seminars: Genetics and Development 1 Unit

Terms offered: Fall 2016, Fall 2010, Spring 2007
The Berkeley Seminar Program has been designed to provide new students with the opportunity to explore an intellectual topic with a faculty member in a small-seminar setting. Berkeley Seminars are offered in all campus departments, and topics vary from department to department and semester to semester.

Freshman Seminars: Genetics and Development: Read More [+]

MCELLBI 90D Freshman Seminars: Immunology 1 Unit

Terms offered: Fall 2017, Fall 2016, Spring 2014
The Berkeley Seminar Program has been designed to provide new students with the opportunity to explore an intellectual topic with a faculty member in a small-seminar setting. Berkeley Seminars are offered in all campus departments, and topics vary from department to department and semester to semester.

Freshman Seminars: Immunology: Read More [+]

MCELLBI 90E Freshman Seminars: Neurobiology 1 Unit

Terms offered: Fall 2017, Spring 2017, Spring 2016
The Berkeley Seminar Program has been designed to provide new students with the opportunity to explore an intellectual topic with a faculty member in a small-seminar setting. Berkeley Seminars are offered in all campus departments, and topics vary from department to department and semester to semester.

Freshman Seminars: Neurobiology: Read More [+]

MCELLBI 91D Immunology 2 - 4 Units

Terms offered: Prior to 2007
Freshman and sophomore seminars offer lower division students the opportunity to explore an intellectual topic with a faculty member and a group of peers in a small-seminar setting. These seminars are offered in all campus departments; topics vary from department to department and from semester to semester.

Immunology: Read More [+]

MCELLBI C96 Studying the Biological Sciences 1 Unit

Terms offered: Fall 2017, Fall 2016, Fall 2015
Freshmen will be introduced to the "culture" of the biological sciences, along with an in-depth orientation to the academic life and the culture of the university as they relate to majoring in biology. Students will learn concepts, skills, and information that they can use in their major course, and as future science professionals. Restricted to freshmen in the biology scholars program.

Studying the Biological Sciences: Read More [+]

MCELLBI 98 Directed Group Study 1 - 4 Units

Terms offered: Spring 2017, Spring 2016, Fall 2015
Lectures and small group discussions focusing on topics of interest, varying from semester to semester.

Directed Group Study: Read More [+]

MCELLBI 99 Supervised Independent Study 1 - 4 Units

Terms offered: Spring 2012, Fall 2009, Spring 2009

Supervised Independent Study: Read More [+]

MCELLBI 100B Biochemistry: Pathways, Mechanisms, and Regulation 4 Units

Terms offered: Spring 2017, Spring 2016, Spring 2015
We survey cellular metabolic pathways, with focus on the underlying chemistry, bioenergetics, and mechanisms. We discuss signaling in the context of a physical chemical understanding of diffusion, transport and molecular interactions. We will highlight the intertwining of signaling and dysregulation with metabolic disorders and cancer, and the production of renewable chemicals such as biofuels. The course is designed for majors in the biochemistry
and molecular biology, genetics and development, or immunology emphases.
Biochemistry: Pathways, Mechanisms, and Regulation: Read More [+]

MCELLBI C100A Biophysical Chemistry: Physical Principles and the Molecules of Life 4 Units

Terms offered: Fall 2017, Spring 2017, Fall 2016
Thermodynamic and kinetic concepts applied to understanding the chemistry and structure of biomolecules (proteins, DNA, and RNA). Molecular distributions, reaction kinetics, enzyme kinetics. Bioenergetics, energy transduction, and motor proteins. Electrochemical potential, membranes, and ion channels.

Biophysical Chemistry: Physical Principles and the Molecules of Life: Read More [+]

MCELLBI 102 Survey of the Principles of Biochemistry and Molecular Biology 4 Units

Terms offered: Fall 2017, Summer 2017 8 Week Session, Spring 2017
A comprehensive survey of the fundamentals of biological chemistry, including the properties of intermediary metabolites, the structure and function of biological macromolecules, the logic of metabolic pathways (both degradative and biosynthetic) and the molecular basis of genetics and gene expression.

Survey of the Principles of Biochemistry and Molecular Biology: Read More [+]

MCELLBI C103 Bacterial Pathogenesis 3 Units

Terms offered: Spring 2017, Spring 2016, Spring 2015, Spring 2014
This course for upper division and graduate students will explore the molecular and cellular basis of microbial pathogenesis. The course will focus on model microbial systems which illustrate mechanisms of pathogenesis. Most of the emphasis will be on bacterial pathogens of mammals, but there will be some discussion of viral and protozoan pathogens. There will be an emphasis on experimental approaches. The course will also include
some aspects of bacterial genetics and physiology, immune response to infection, and the cell biology of host-parasite interactions.
Bacterial Pathogenesis: Read More [+]

MCELLBI 104 Genetics, Genomics, and Cell Biology 4 Units

Terms offered: Fall 2017, Spring 2017, Fall 2016
This course will introduce students to key concepts in genetic analysis, eukaryotic cell biology, and state-of-the-art approaches in genomic medicine. Lectures will highlight basic knowledge of cellular processes with the basis for human diseases, particularly cancer. Prerequisite courses will have introduced students to the concepts of cells, the central dogma of molecular biology, and gene regulation. Emphasis in this course will be on eukaryotic
cell processes, including cellular organization, dynamics, and signaling.
Genetics, Genomics, and Cell Biology: Read More [+]

MCELLBI 110 Molecular Biology: Macromolecular Synthesis and Cellular Function 4 Units

Terms offered: Fall 2017, Spring 2017, Fall 2016
Molecular biology of prokaryotic and eukaryotic cells and their viruses. Mechanisms of DNA replication, transcription, translation. Structure of genes and chromosomes. Regulation of gene expression. Biochemical processes and principles in membrane structure and function, intracellular trafficking and subcellular compartmentation, cytoskeletal architecture, nucleocytoplasmic transport, signal transduction mechanisms, and cell cycle control.

Molecular Biology: Macromolecular Synthesis and Cellular Function: Read More [+]

MCELLBI C110L General Biochemistry and Molecular Biology Laboratory 4 Units

Terms offered: Fall 2017, Spring 2017, Fall 2016
Experimental techniques of biochemistry and molecular biology, designed to accompany the lectures in Molecular and Cell Biology 100B and 110.

General Biochemistry and Molecular Biology Laboratory: Read More [+]

MCELLBI C112 General Microbiology 4 Units

Terms offered: Fall 2017, Summer 2017 10 Week Session, Fall 2016
This course will explore the molecular bases for physiological and biochemical diversity among members of the two major domains, Bacteria and Archaea. The ecological significance and evolutionary origins of this diversity will be discussed. Molecular, genetic, and structure-function analyses of microbial cell cycles, adaptive responses, metabolic capability, and macromolecular syntheses will be emphasized.

General Microbiology: Read More [+]

MCELLBI C112L General Microbiology Laboratory 2 Units

Terms offered: Fall 2017, Summer 2017 10 Week Session, Spring 2017
Experimental techniques of microbiology designed to accompany the lecture in C112 and C148. The primary emphasis in the laboratory will be on the cultivation and physiological and genetic characterization of bacteria. Laboratory exercises will include the observation, enrichment, and isolation of bacteria from selected environments.

General Microbiology Laboratory: Read More [+]

MCELLBI C114 Introduction to Comparative Virology 4 Units

Terms offered: Spring 2017, Spring 2016, Spring 2015
This course will provide a comparative overview of virus life cycles and strategies viruses use to infect and replicate in hosts. We will discuss virus structure and classification and the molecular basis of viral reproduction, evolution, assembly, and virus-host interactions. Common features used during virus replication and host cellular responses to infection will be covered. Topics also included are common and emerging virus diseases
, their control, and factors affecting their spread.
Introduction to Comparative Virology: Read More [+]

MCELLBI C116 Microbial Diversity 3 Units

Terms offered: Fall 2017, Fall 2016, Fall 2015
This course for upper-division and graduate students will broadly survey myriad types of microbial organisms, both procaryote and eucaryote, using a phylogenetic framework to organize the concept of "biodiversity." Emphasis will be on the evolutionary development of the many biochemical themes, how they mold our biosphere, and the organisms that affect the global biochemistry. Molecular mechanisms that occur in different lineages will
be compared and contrasted to illustrate fundamental biological strategies. Graduate students additionally should enroll in C216, Microbial Diversity Workshop.
Microbial Diversity: Read More [+]

MCELLBI 118 The Cancer Karyotype: What it is and What it Does 1 Unit

Terms offered: Fall 2017, Spring 2017, Fall 2016
Mutational cancer theories do not explain why cancers: 1) have clonal individual karyotypes; 2) have polygenic transcriptomes and phenotypes; 3) have flexible karyotypes, which evolve progressive malignancy and drug resistance, but maintain autonomy and even immortality; and 4) Why carcinogens induce cancer only after conspicuously long latent periods of years to decades. To answer these questions, this course tests a new karyotypic theory, which
postulates that cancers evolve much like new species.
The Cancer Karyotype: What it is and What it Does: Read More [+]

MCELLBI 130 Cell and Systems Biology 4 Units

Terms offered: Spring 2017, Fall 2009, Spring 2009
This course will provide a detailed discussion of a wide range of topics in cell biology emphasizing experimental approaches and key experiments that have provided important insights. The course is aimed at conveying an understanding of how cellular structure and function arise as a result of the properties of cellular macromolecules. An emphasis will be placed on the dynamic nature of cellular organization and will include a description of
physical properties of cells (dimensions, concepts of free energy, diffusion, biophysical properties). Students will be introduced to quantitative aspects of cell biology and a view of cellular function that is based on integrating multiple pathways and modes of regulation (systems biology).
Cell and Systems Biology: Read More [+]

MCELLBI 132 Biology of Human Cancer 4 Units

Terms offered: Fall 2017, Fall 2016, Fall 2015
The course is designed for students interested in learning about the molecular and cell biology of cancer and how this knowledge is being applied to the prevention, diagnosis and therapy of cancer. Topics covered include tumor pathology and epidemiology; tumor viruses and oncogenes; intracellular signaling; tumor suppressors; multi-step carcinogenesis and tumor progression; genetic instability in cancer; tumor-host interactions; invasion and metastasis;
tumor immunology; cancer therapy.
Biology of Human Cancer: Read More [+]

MCELLBI 133L Physiology and Cell Biology Laboratory 4 Units

Terms offered: Fall 2017, Spring 2017, Fall 2016
Experimental analyses of central problems in cell biology and physiology using modern techniques, including DNA cloning and protein biochemistry, fluorescence microscopy of the cytoskeleton and organelles, DNA transfection and cell cycle analysis of cultured mammalian cells, RNA interference and drug treatments to analyze ion channel function in cell contractility and intracellular signaling, and somatosensation.

Physiology and Cell Biology Laboratory: Read More [+]

MCELLBI C134 Chromosome Biology/Cytogenetics 3 Units

Terms offered: Spring 2016, Spring 2015, Spring 2014
Survey of behavior, structure, and function of chromosomes with emphasis on behavior in model organisms. Topics include mitosis, meiosis, chromosome aberrations, genome function, dosage compensation, transposons, repetitive DNA, and modern cytological imaging.

Chromosome Biology/Cytogenetics: Read More [+]

MCELLBI 135A Topics in Cell and Developmental Biology: Molecular Endocrinology 3 Units

Terms offered: Fall 2017, Fall 2016, Fall 2015
Molecular mechanisms by which hormones elicit specific responses and regulate gene expression; hormone-receptor interaction; synthesis, transport and targeting of hormones, growth factors and receptors.

Topics in Cell and Developmental Biology: Molecular Endocrinology: Read More [+]

MCELLBI 136 Physiology 4 Units

Terms offered: Fall 2017, Fall 2016, Fall 2015
Principles of mammalian (primarily human) physiology emphasizing physical, chemical, molecular and cellular bases of functional biology. The following topics will be covered: cellular and membrane ion and nonelectrolyte transport; cell and endocrine regulation; autonomic nervous system regulation; skeletal, smooth and cardiac muscle; cardiovascular physiology; respiration; renal physiology; gastrointestinal physiology. Discussion section led by
Graduate Student Instructor will review material covered in lecture.
Physiology: Read More [+]

MCELLBI 137L Physical Biology of the Cell 3 Units

Terms offered: Spring 2017
Biology is being revolutionized by new experimental techniques that have made it possible to measure the inner workings of molecules, cells and multicellular organisms with unprecedented precision. The objective of this course is to explore this deluge of quantitative data through the use of biological numeracy. We will develop theoretical models that make precise predictions about biological phenomena. These predictions will be tested through the hands-on analysis
of experimental data and by performing numerical simulations using Matlab.

Physical Biology of the Cell: Read More [+]

MCELLBI 140 General Genetics 4 Units

Terms offered: Fall 2017, Spring 2017, Fall 2016
In-depth introduction to genetics, including mechanisms of inheritance; gene transmission and recombination; transposable DNA elements; gene structure, function, and regulation; and developmental genetics. Some exams may be given in the evening.

General Genetics: Read More [+]

MCELLBI 140L Genetics Laboratory 4 Units

Terms offered: Spring 2017, Spring 2016, Spring 2015
Experimental techniques in classical and molecular genetics.

Genetics Laboratory: Read More [+]

MCELLBI 141 Developmental Biology 4 Units

Terms offered: Spring 2017, Spring 2016, Spring 2015
An introduction to principles and processes of embryonic and post-embryonic development, stressing mechanisms of cell and tissue interactions, morphogenesis and regulation of gene expression.

Developmental Biology: Read More [+]

MCELLBI 143 Evolution of Genomes, Cells, and Development 3 Units

Terms offered: Fall 2016, Fall 2015, Fall 2014
This course is intended for upper-division undergraduates seeking an interactive course based on modern concepts in evolution and comparative genomics. The course will emphasize the contribution of molecular evolution to a series of seminal events in life's history: origin of life; origin of cells; origin of eukaryotes; origin of multicellularity; evolution of animal development; human origins.

Evolution of Genomes, Cells, and Development: Read More [+]

MCELLBI C148 Microbial Genomics and Genetics 4 Units

Terms offered: Spring 2017, Spring 2016, Spring 2015
Course emphasizes bacterial and archaeal genetics and comparative genomics. Genetics and genomic methods used to dissect metabolic and development processes in bacteria, archaea, and selected microbial eukaryotes. Genetic mechanisms integrated with genomic information to address integration and diversity of microbial processes. Introduction to the use of computational tools for a comparative analysis of microbial genomes and determining relationships
among bacteria, archaea, and microbial eukaryotes.
Microbial Genomics and Genetics: Read More [+]

MCELLBI 149 The Human Genome 3 Units

Terms offered: Spring 2016, Spring 2015, Spring 2014
This is an upper division course for majors in MCB with an interest in an in-depth exploration of the forces that shape the human genome and the human population, as well as the ways that human genetic information can be used in medicine, ancestry and forensics. The course will combine lectures and discussion of research papers.

The Human Genome: Read More [+]

MCELLBI 150 Molecular Immunology 4 Units

Terms offered: Fall 2017, Spring 2017, Fall 2016
Fundamentals of immunology with emphasis on biochemical and molecular approaches to study of the immune system and its application in medicine and biotechnology. Topics covered include description of the immune system, antibody and T-cell receptor structure and function, genes of the immunoglobulin superfamily, cells and molecular mediators that regulate the immune response, allergy, autoimmunity, immunodeficiency, tissue and organ transplants
, and tumor immunology.
Molecular Immunology: Read More [+]

MCELLBI 150L Immunology Laboratory 4 Units

Terms offered: Fall 2017, Spring 2017, Fall 2016
Experimental techniques in mammalian molecular biology and cellular immunology. Molecular techniques covered include PCR and recombinant DNA procedures such as gene cloning, gene transfer, DNA sequencing, Southern blot, and restriction mapping. Immunological techniques covered include cell culture and monoclonal antibody production, flow cytometry, ELISA, immunoprecipitation, and western blot.

Immunology Laboratory: Read More [+]

MCELLBI 160 Cellular and Molecular Neurobiology 4 Units

Terms offered: Fall 2017, Fall 2016, Fall 2015
Comprehensive introductory survey of cellular and molecular neuroscience, including cellular neurophysiology, ion channel function, synaptic function and plasticity, sensory transduction, and brain development. Includes introduction to molecular basis of neurological disease. Analysis from the level of molecules to cells to simple circuits.

Cellular and Molecular Neurobiology: Read More [+]

MCELLBI 160L Neurobiology Laboratory 4 Units

Terms offered: Spring 2017, Spring 2016, Spring 2015
Experimental analyses of properties and interactions of nerve cells and systems, illustrating principal features and current methods. Techniques employed include computer simulation of neuron properties, electrophysiological recording and stimulation of nerves and cells, digitally enhanced video imaging of outgrowth, fluorescence immunocytochemistry, analysis of sensory: CNS mapping, human-evoked potential recording, sensory psychophysics.

Neurobiology Laboratory: Read More [+]

MCELLBI 161 Circuit, Systems and Behavioral Neuroscience 4 Units

Terms offered: Spring 2017, Spring 2016
Comprehensive survey of circuits and systems neuroscience, including sensory and motor systems, learning and memory, neuromodulatory systems and brain state and higher functions.
Biological and computational principles of neural circuit function. Analysis from the level of small circuits to behavior.

Circuit, Systems and Behavioral Neuroscience: Read More [+]

MCELLBI 163L Mammalian Neuroanatomy Lab 4 Units

Terms offered: Fall 2017, Fall 2016
Development, structure (gross and microscopic), and functional relationships of the mammalian nervous system.

Mammalian Neuroanatomy Lab: Read More [+]

MCELLBI 165 Neurobiology of Disease 3 Units

Terms offered: Spring 2017, Spring 2016, Spring 2015
The molecular, cellular, and neural circuit basis of neurological disease. Includes neurochemistry and reward systems, neural development and its disorders, addiction, neurodegenerative and neuropsychiatric disorders. Students will read and discuss primary papers from the research literature.

Neurobiology of Disease: Read More [+]

MCELLBI 166 Biophysical Neurobiology 3 Units

Terms offered: Fall 2017, Fall 2016, Fall 2015
Electrochemistry and ion transport phenomena, equivalent circuits, excitability, action potentials, voltage clamp and the Hodgkin-Huxley model. Biophysical properties of ion channels. Statistical and electrophysiological models of synaptic transmission, Quantitative models for dendritic structure and neuronal morphogenesis. Sensory transduction, cellular networks as computational devices, information processing and transfer.

Biophysical Neurobiology: Read More [+]

MCELLBI 180 Undergraduate Teaching of Biology 1A Laboratory 1 or 2 Units

Terms offered: Spring 2012, Spring 2007, Fall 2006
Course consists of a weekly three-hour training session that focuses on laboratory techniques, instructional aids, and problem solving, plus an additional three hour weekly laboratory where the UGSI is required to assist a GSI in the instruction of laboratory (answering questions, providing demonstrations, etc.).

Undergraduate Teaching of Biology 1A Laboratory: Read More [+]

MCELLBI 180C Undergraduate Teaching of Molecular and Cell Biology 32 Laboratory 1 - 2 Units

Terms offered: Fall 2012, Fall 2011, Fall 2010
Course consists of a weekly three-hour training session that focuses on laboratory techniques, instructional aids, and problem solving, plus an additional three-hour weekly laboratory where the UGSI is required to assist a GSI in the instruction of laboratory (answering questions, providing demonstrations, etc.). Students will be graded on lecture and laboratory attendance and preparation of one quiz.

Undergraduate Teaching of Molecular and Cell Biology 32 Laboratory: Read More [+]

MCELLBI N184 IGI CRISPR Workshop: Practical Aspects of Precision Biology for Undergraduates 1 Unit

Terms offered: Summer 2017 3 Week Session
This 1-week workshop will focus on applications of CRISPR technology as a platform for genome editing and functional genomics. The program will consist of lectures from experts in the field and a hands-on laboratory experience demonstrating targeted mutagenesis in cultured human cells. Workshop faculty will address topics in genome editing and CRISPR-Cas9 research, including basic and enhanced CRISPR methods, cellular repair mechanisms, regulation of
gene expression, bioinformatics, applications to various organisms, and bioethics.
IGI CRISPR Workshop: Practical Aspects of Precision Biology for Undergraduates: Read More [+]

MCELLBI 194 Undergraduate Student Instructor for Molecular and Cell Biology Courses 1 - 2 Units

Terms offered: Prior to 2007
UGSIs will work under supervision of instructor and/or GSI. The UGSI will attend three hours of lecture per week and one hour or two hours of discussion section a
week depending on the number of units, where they will assist a GSI in instruction (answering questions, providing demonstrations, facilitating activities, etc.). In addition, UGSIs
will meet with students from their section for one or two hours of tutoring per week depending on the number of
units. UGSIs do not evaluate students' work or assign grades. UGSIs will be
graded on lecture and discussion attendance and preparation of one lesson plan and one quiz. Required to attend any mandatory preparatory and review meetings.

Undergraduate Student Instructor for Molecular and Cell Biology Courses: Read More [+]

MCELLBI H196A Honors Research 1 - 4 Units

Terms offered: Fall 2015, Fall 2014, Spring 2013
Individual research and thesis preparation under the supervision of a faculty member. Acceptance to the Molecular and Cell Biology Honors Program is required. Contact the MCB Undergraduate Affairs Office, 3060 Valley Life Sciences Building, for application and details. Honor students must complete at least two semesters of research, taking a minimum of 4 units and a maximum of 8 units of H196A-196B. If desired, one semester of 199 can be used
to replace H196A.
Honors Research: Read More [+]

MCELLBI H196B Honors Research 1 - 4 Units

Terms offered: Spring 2016, Spring 2015, Spring 2014
Individual research and completion of thesis under the supervision of a faculty member. This course satisfies the thesis requirement for the Molecular and Cell Biology Department Honors Program. Contact the MCB Undergraduate Affairs Office, 3060 Valley Life Sciences Building, for program details and an application. Honor students must complete at least two semesters of research, taking a minimum of 4 units and a maximum of 8 units of H196A-196B.
One semester of H196B is required.
Honors Research: Read More [+]

MCELLBI 197 Supervised Internship 1 Unit

Terms offered: Fall 2016
Supervised experience relevant to specific topics of biology in off-campus organizations. Written report and evaluation from internship supervisor required.

Supervised Internship: Read More [+]

MCELLBI 198 Directed Group Study 1 - 4 Units

Terms offered: Spring 2017, Fall 2016, Spring 2016
Lectures and small group discussions focusing on topics of interest, varying from semester to semester.

Directed Group Study: Read More [+]

MCELLBI 199 Supervised Independent Study and Research 1 - 4 Units

Terms offered: Fall 2015, Spring 2015, Fall 2014
Enrollment restrictions apply; see the Introduction to Courses and Curricula section of this catalog.

Supervised Independent Study and Research: Read More [+]

Faculty and Instructors

+ Indicates this faculty member is the recipient of the Distinguished Teaching Award.

Faculty

Hillel Adesnik, Assistant Professor.

Georjana Barnes, Professor. Biochemistry, genetics, cancer, biology, microtubule cytoskeleton, cell cycle controls, cellular imaging.
Research Profile

Gregory M. Barton, Professor. Immunology, cell biology, infectious disease, innate immunity.
Research Profile

Helen Bateup, Assistant Professor. Molecular and cellular neuroscience, neurodevelopmental disorders, autism, epilepsy.
Research Profile

Diana Bautista, Associate Professor. Ion channels, sensory physiology, chemosensation, touch, thermosensation, somatosensory system.
Research Profile

David Bilder, Professor. Genetics, cancer, Drosophila, cell biology, cell polarity, tumor suppressor, epithelial architecture, polarity, and proliferation control.
Research Profile

Michael R. Botchan, Professor. Eukaryotic gene expression, drosophila chromosomes, papilloma viral DNA, chromosomal dynamics.
Research Profile

Gloria Brar, Assistant Professor. Meiosis, translation, sORFs, stress responses.
Research Profile

Steve Brohawn, Assistant Professor.
Research Profile

Carlos J. Bustamante, Professor. Nanoscience, structural characterization of nucleo-protein assemblies, single molecule fluorescence microscopy, DNA-binding molecular motors, the scanning force microscope, prokaryotes.
Research Profile

Jamie Cate, Professor. Molecular basis for protein synthesis by the ribosome, RNA, antibiotics, a thermophilic bacterium, escherichia coli.
Research Profile

Christopher J. Chang, Professor. Chemistry, inorganic chemistry, neuroscience, bioinorganic chemistry, general physiology, organic chemistry, new chemical tools for biological imaging and proteomics, new metal complexes for energy catalysis and green chemistry, chemical biology.
Research Profile

Michelle Chang, Associate Professor.

Kathleen Collins, Professor. RNA, telomerase, Telomere function, Telomere replication.
Research Profile

Jacob E. Corn, Assistant Adjunct Professor.

Laurent Coscoy, Associate Professor. Immunology, viruses, viral infection, immune responses, immune evasion.
Research Profile

Jeffery S. Cox, Professor.

Yang Dan, Professor. Neuronal circuits, mammalian visual system, electrophysiological, psychophysical and computational techniques, visual cortical circuits, visual neurons.
Research Profile

Xavier Darzacq, Assistant Professor.

Abby Dernburg, Professor. Genomics, chromosome remodeling and reorganization during meiosis, Down syndrome, DNA.
Research Profile

Andrew Dillin, Professor.

Jennifer A. Doudna, Professor. RNA machines, hepatitis C virus, RNA interference, ribosomes.
Research Profile

David G. Drubin, Professor. Cellular morphogenesis, plasma membrane dynamics, microtubule cytoskeletons, cytoskeletal proteins, morphological development.
Research Profile

Peter H. Duesberg, Professor. Genetic structure of retroviruses, carcinogenesis, aneuploidy, virology, HIV-AIDS.
Research Profile

Michael B. Eisen, Professor. Genomics, genome sequencing, bioinformatics, animal development.
Research Profile

+ Dan Feldman, Associate Professor. Neurobiology, learning, neurophysiology, sensory biology.
Research Profile

Marla B. Feller, Professor. Neurophysiology, developmental neuroscience.
Research Profile

+ Gary L. Firestone, Professor. Cancer, steroid hormones, molecular endocrinology, tumor biology, growth factors, dietary compounds, tumor cells, glucocorticoids.
Research Profile

John Gerard Flannery, Professor. Neurobiology, optometry, vision science, cell and molecular biology of the retina in normal and diseased states.
Research Profile

Hernan G. Garcia, Assistant Professor.

Gian Garriga, Professor. Developmental neurobiology; molecular genetics, development of nervous systems, cell division, cell migration, axonal pathfinding, caenorhabditis elegans.
Research Profile

Britt Glaunsinger, Associate Professor. Virology, gene expression, herpesvirus.
Research Profile

Ming Chen Hammond, Assistant Professor. Molecular biology, biochemistry, organic chemistry, synthetic biology, chemical biology.
Research Profile

Iswar Krishna Hariharan, Professor. Growth regulation, regeneration, cancer.
Research Profile

Richard M. Harland, Professor. Molecular biology, early vertebrate development, Xenopus, embryo development.
Research Profile

Lin He, Associate Professor.

Rebecca Heald, Professor. Cell division, Xenopus, mitotic spindle assembly and function, size control of intracellular structures.
Research Profile

Dirk Hockemeyer, Assistant Professor.

James Hurley, Professor.

Nicholas Ingolia, Assistant Professor. Ribosome Profiling, translation, genomics.
Research Profile

Ehud Y. Isacoff, Professor. Ion channel function, synaptic plasticity, neural excitability, synaptic transmission, the synapse.
Research Profile

Gary H. Karpen, Adjunct Professor. Gene expression, cell biology, chromosome structure and function, drosophila melanogaster, centromere identity and function.
Research Profile

Nicole King, Professor. Genetics, developmental biology, biology, choanoflagellates, multicellularity, evolution of animals, comparative genomics, eukaryotes, host-microbe interactions, bacterial signals.
Research Profile

Douglas E. Koshland, Professor. Higher order chromosome structure, genome integrity, sister chromatid cohesion, chromosome condensation, desiccation tolerance, microbial genetics.
Research Profile

Richard H. Kramer, Professor. Cells, synaptic transmission, chemical signaling between neurons, ion channels, electrical signals, chemical reagents, synapses.
Research Profile

John Kuriyan, Professor. Structural and functional studies of signal transduction, DNA replication, cancer therapies, phosphorylation.
Research Profile

Stephan Lammel, Assistant Professor. Neuroscience, Optogenetics, dopamine, addiction, depression.
Research Profile

Michael S. Levine, Professor. Regulation of enhancer-promoter interactions, gene networks, animal development and disease, drosophila embryo, immune response in drosophila larvae, differentiation of the notochord and heart in the sea squirt, whole-genome analysis.
Research Profile

Polina Lishko, Assistant Professor. Reproductive and Developmental Biology, ion channels, Physiology of Fertilization and Early Embryo Development.
Research Profile

Kunxin Luo, Professor. Signal transduction pathways, mechanisms controlling the receptor kinases, regulation of mammary epithelial cell differentiation, breast carcinogenesis.
Research Profile

Terry Machen, Professor. Physiology pathophysiology secretory epithelial cells, airway, ion transport, cell regulationm, imaging microscopy, calcium pH redox, electrophysiology, green fluorescent protein, genetic targeting, innate immune defense.
Research Profile

Michael A. Marletta, Professor. Chemical biology, molecular biology, structure/function relationships in proteins, catalytic and biological properties of enzymes, cellular signaling, nitric oxide synthase, soluble guanylate cyclase, gas sensing, cellulose degradation, polysaccharide monooxygenases.
Research Profile

Susan Marqusee, Professor. Amino acids, determinants of protein structure and folding, biophysical, structural and computational techniques, translocation, protein synthesis.
Research Profile

Andreas Martin, Associate Professor. Proteasome.
Research Profile

G. Steven Martin, Professor. Cell biology, signal transduction pathways, tumor virology, cell division cycle, viral and cellular oncoproteins, breast cancer.
Research Profile

Barbara J. Meyer, Professor. Developmental biology, gene expression, genetic determination of sex, regulatory genes, chromosome dynamics, X-chromosome.
Research Profile

Craig Miller, Assistant Professor. Genetics, developmental biology, evolutionary biology, evolution, quantitative genetics, developmental genetics, evolutionary genetics, craniofacial development.
Research Profile

Evan W. Miller, Assistant Professor.

John Ngai, Professor. Nervous system, molecular and cellular mechanisms of olfaction, detection of odors, odorant receptors, olfactory neurons, DNA microarray technologies, genome-wide patterns of gene expression.
Research Profile

Eva Nogales, Professor. Biochemistry, complex biological assemblies, structure and regulation of the cytoskeleton, microtubule dynamics, human transcriptional initiation machinery, biophysics.
Research Profile

George Oster, Professor. Computational biology, developmental biology, mathematical modeling of molecular and cellular systems, protein motors, cell motility, spatial pattern formation in eukaryotic and prokaryotic cells, neural pattern formation.
Research Profile

Lior Pachter, Professor. Mathematics, applications of statistics, combinatorics to problems in biology.
Research Profile

Nipam Patel, Professor. Genetics, evolution, crustaceans, insects, arthropods, homeotic (Hox) genes, segmentation, embryonic pattern formation, neural patterning.
Research Profile

Mu-Ming Poo, Professor. Neurobiology, cellular and molecular mechanisms, axon guidance, synapse formation, activity-dependent refinement of neural circuits.
Research Profile

Daniel A. Portnoy, Professor. Mammalian cells, molecular and cellular basis of microbial pathogenesis, defense against infection, listeria monocytogenes, cell biology of infection, mechanisms of secretion.
Research Profile

Michael Rape, Professor. Cancer, protein degradation, siRNA, Berkeley Screening Center.
Research Profile

David H. Raulet, Professor. Biology, pathogens, viruses, T-cell development and function, natural killer (NK) cells, lymphocyte receptors, microorganisms, cancer cells, tumor immunity.
Research Profile

+ Jasper D. Rine, Professor. Biology, cell biology, DNA replication, gene regulation, saccharomyces cerevisiae, genetic analysis, genome, cholesterol biosynthetic pathway, modification of proteins, prenylated proteins.
Research Profile

Donald C. Rio, Professor. Molecular genetics, drosophila melanogaster, transposable elements, RNA splicing, nucleic acid rearrangement reactions, P elements and their cellular host, HIV, proteomic diversification, nucleoprotein complexes.
Research Profile

Ellen Robey, Professor. Fate determination in the T-lymphocyte lineage, T cell development in the mouse, thymic development, cellular maturation, parasitic infection, chronic infection, host-pathogen interactions, Toxoplasma gondii.
Research Profile

Henk Roelink, Associate Professor. Stem cells, neural development, embryonic induction.
Research Profile

Daniel S. Rokhsar, Professor. Biology, collective phenomena and ordering in condensed matter and biological systems, theoretical modeling, computational modeling, behavior of quantum fluids, cold atomic gases, high temperature superconductors, Fermi and Bose systems.
Research Profile

Kaoru Saijo, Assistant Professor.

David Savage, Assistant Professor. Synthetic biology and metabolism.
Research Profile

David Schaffer, Professor. Neuroscience, biomolecular engineering, bioengineering, stem cell biology, gene therapy.
Research Profile

Randy W. Schekman, Professor. Saccharomyces cerevisiae, organelle assembly, intracellular protein transport, assembly of cellular organelles, Alzheimer's Disease.
Research Profile

Kristin Scott, Professor. Nerve cell connectivity in developing nervous systems, taste perception in the fruit fly, taste neural circuits, sensory maps in the brain.
Research Profile

Bill Sha, Associate Professor. B cell gene regulation, fate determination, gene regulatory pathways, antibody-secreting plasma cells, memory B cells, apoptotic cells, B7 costimulatory ligands.
Research Profile

+ Nilabh Shastri, Professor. Cancer cells, mechanims of immunesurveillance, microbial pathogens, antigen genes, autoimmunity.
Research Profile

Sarah Stanley, Assistant Professor.

Jeremy W. Thorner, Professor. Biochemistry, molecular genetics, cell biology, signal transduction mechanisms, protein kinase function and regulation, GPCRs, membrane biology, control of cell growth/morphology and division, regulation of gene expression by extracellular stimuli.
Research Profile

Robert T. Tjian, Professor. Eukaryotic molecular biology; biochemistry, cellular differentiation, chromatin function, RNA synthesis, single cell imaging, single molecule imaging.
Research Profile

Elcin Unal, Assistant Professor.

Fyodor Urnov, Associate Adjunct Professor.

Russell E. Vance, Professor. Immunology, microbiology, infectious disease, molecular and cell biology.
Research Profile

David A. Weisblat, Professor. Annelid developmental biology, leech embryo, evolution & development, cell fate determination, lineage tracingt.
Research Profile

Matthew D. Welch, Professor. Biology, cell motility, the role of the actin cytoskeleton in cell locomotion, shape change, actin filament assembly, bacterial and viral pathogens.
Research Profile

Astar Winoto, Professor. Cancer, genomics, apoptosis, innate immunity and infectious diseases, cell cycle, signal transduction, immune tolerance.
Research Profile

Ahmet Yildiz, Assistant Professor. Single molecule biophysics, molecular motors, telomeres.
Research Profile

Qiang Zhou, Professor. Biochemistry of HIV gene expression, transcriptional elongation, Tat activation, stage of transcriptional elongation, HIV replication, anti-HIV therapy.
Research Profile

Roberto Zoncu, Assistant Professor.

Lecturers

Robin W. Ball, Lecturer.

P. Robert Beatty, Lecturer.

Natalia Caporale, Lecturer.

Isabelle Le Blanc, Lecturer.

Helen Lew, Lecturer.

David E. Presti, Senior Lecturer SOE.

Steve Takata, Lecturer.

Gary Joseph Wedemayer, Lecturer.

Visiting Faculty

Tamira M. Elul, Visiting Associate Professor.

Emeritus Faculty

Mark Alper, Professor Emeritus.

Bruce N. Ames, Professor Emeritus. Molecular biology, cancer, aging, mitochondrial decay, oxidants and antioxidants, micronutrient deficiencies and DNA damage, chronic inflammation and cancer.
Research Profile

Giovanna F.-L. Ames, Professor Emeritus.

Clinton E. Ballou, Professor Emeritus.

Steven K. Beckendorf, Professor Emeritus. Genetics, biology, organogenesis, Drosophila, salivary morphogenesis.
Research Profile

David R. Bentley, Professor Emeritus.

Phyllis B. Blair, Professor Emeritus.

Beth Burnside, Professor Emeritus. Cell biology of photoreceptors, cytoskeletal motors, morphogenetic events, photomembrane turnover.
Research Profile

Richard Calendar, Professor Emeritus. Listeria monocytogenes, phage-based integration vector, Bacillus anthracis, vaccine.
Research Profile

W. Zacheus Cande, Professor Emeritus. Genetics, cell biology, microbial biology, plant biology.
Research Profile

M. J. Chamberlin, Professor Emeritus.

Alvin J. Clark, Professor Emeritus.

Thomas W. Cline, Professor Emeritus. Drosophila melanogaster, developmental genetics, sex determination.
Research Profile

R. David Cole, Professor Emeritus.

John Gerhart, Professor Emeritus. Developmental biology, Xenopus laevis, Spemann's organizer, cortical rotation, cell cycle after fertilization, vegetal materials, blastula stage, egg cytoplasm.
Research Profile

Robert M. Glaeser, Professor Emeritus.

Alexander N. Glazer, Professor Emeritus. Photosynthetic systems, phycobiliproteins, design of fluorescent probes, protein structure-function relationships, macromolecular complexes, environmental sciences, natural resource management.
Research Profile

Stuart M. Linn, Professor Emeritus. Biology, enzymology of DNA metabolism, DNA repair and replication in mammalian cells, mechanisms of DNA damage by reactive oxygen species, structure of iron: DNA complexes, DNA damage and repair, DNA polymerases.
Research Profile

Robert I. Macey, Professor Emeritus.

Howard C. Mel, Professor Emeritus.

Hsiao-Ping H. Moore, Professor Emeritus.

Satyabrata Nandi, Professor Emeritus.

Alexander V. Nichols, Professor Emeritus.

Hiroshi Nikaido, Professor Emeritus. Membrane biochemistry, bacterial physiology, bacteria, channel-forming proteins of the outer membrane, the diffusion of lipophilic compounds, mechanism and regulation of multidrug efflux transport systems, mycobacterial cell wall.
Research Profile

W. Geoffrey Owen, Professor Emeritus. Biology, nervous system, membrane biophysics, retinal neurophysiology.
Research Profile

Edward E. Penhoet, Professor Emeritus. Public health, health policy and management.
Research Profile

Gerald M. Rubin, Professor Emeritus. Molecular genetics, molecular neurobiology, mapping and sequencing of the drosophila genome, genome organization and function, development and evolution.
Research Profile

Harry Rubin, Professor Emeritus. Tumor biology, cell biology, regulation of neoplastic development, epithelial cells, oncogenic mutations, tumor development, RNA and DNA tumor viruses.
Research Profile

Howard K. Schachman, Professor Emeritus. Physical biochemistry, biological macromolecules, aspartate transcarbamylase, revisiting allostery, holoenzyme, mutations, polypeptide chains, helical regions.
Research Profile

Herbert H. Srebnik, Professor Emeritus.

Frank S. Werblin, Professor Emeritus. Retina, biological image processing, visual neuroscience.
Research Profile

Gerald Westheimer, Professor Emeritus. Neurobiology; psychophysics, primate visual cortex, neural circuits, brain mechanisms, response modifications, active perception, learning, stereoscopic vision, optometryoptics of the eye, ophthalmic instrumentation.
Research Profile

Fred H. Wilt, Professor Emeritus. Molecular embryology; cell biology, the regulation of gene expression, of sea urchin embryos, blastomeres, endoskeletal spicule of the larva, glycoproteins, immunoelectron microscopy, fluorescent labeling.
Research Profile

Leon Wofsy, Professor Emeritus.

Robert S. Zucker, Professor Emeritus. Synaptic transmission, cellular neurophysiology; synaptic biophysics, properties of neural circuits, photolysis, vital dyes of vesicle membrane, electrophysiological techniques, neuromodulator.
Research Profile

Contact Information

Department of Molecular and Cell Biology

3060 Valley Life Sciences Bldg

Phone: 510-642-2651

mcbchair@berkeley.edu

Visit Department Website

Undergraduate Advising

Undergraduate Affairs Office

3060 Valley Life Sciences Building

Phone: 510-643-8895

mcbuao@berkeley.edu

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